Savory and Spicy Fish Sandwich Recipe

Greetings, food enthusiasts! Today, I am here to introduce to you a recipe that will take your taste buds to the fiery Southwest. This recipe is perfect for those looking for a quick and easy yet zesty meal: the Southwest Spicy Fish Sandwich.

Picture yourself biting into a crispy fish fillet with a kick of spice and a burst of complementing flavors. This sandwich combines tender tilapia fillets with the rich, smoky flavor of chipotle pepper mayonnaise, tangy cheddar cheese, and fresh romaine lettuce. The combination of these ingredients creates a harmonious symphony in your mouth that’ll leave you craving more.

This recipe is perfect for those busy weeknights or when you’re just in the mood for deliciousness without slaving away in the kitchen. Whether you’re cooking for yourself or entertaining guests, this Southwest Spicy Fish Sandwich Recipe is guaranteed to be a hit.

With just a few simple ingredients that you can easily find in your local grocery store, this recipe is both affordable and practical. Get ready to indulge in the best spicy fish sandwich you’ve ever tasted!

Don’t just take my word for it – let’s dive into the recipe and see why this sandwich is worth adding to your recipe collection.

Why You’ll Love This Recipe

Southwest Spicy Fish Sandwich
Southwest Spicy Fish Sandwich

Are you looking for a way to spice up your lunch or dinner routine? Look no further than this Southwest Spicy Fish Sandwich Recipe. This sandwich is the perfect combination of crispy fish and bold, zesty flavors.

First, let’s talk about the star of the show: the spicy fish fillet. Made with tilapia fillets coated in a delicious blend of chipotle pepper and garlic powder, it packs a punch that will have your taste buds singing. Plus, it can be prepared in multiple ways whether grilled or fried for an added crunch.

But this sandwich isn’t just about the fish. It’s also loaded with fresh Romaine lettuce, cheddar cheese, and a homemade chipotle mayonnaise that is sure to tantalize your taste buds. The mayonnaise gives a much-needed kick to the sandwich and only compliments the fish even more.

And don’t worry about slaving away in the kitchen all day to make this dish possible. The recipe is easy to follow and takes only thirty minutes to prepare. Plus, it’s super versatile – substitute your favorite white fish or add in some sliced tomato for an extra freshness.

But the best part? This Southwest Spicy Fish Sandwich Recipe is perfect pairing with some sweet potato fries or cole slaw. So next time you’re in need of a quick yet satisfying lunch and dinner option look no further than this delicious sandwich recipe – You won’t regret it!

Ingredient List

“This fish sandwich will have your taste buds doing the salsa!”

Ingredients for Southwest Spicy Fish Sandwich Recipe

In order to prepare this spicy fish sandwich, we will need the following ingredients:

  • 4 tilapia fillets
  • 4 large leaves of romaine lettuce
  • 4 large hamburger buns sprinkled with sesame seeds
  • 4 ounces of cheddar cheese, sliced
  • 4 tablespoons of chipotle mayonnaise
  • 1 teaspoon of garlic powder
  • ¼ teaspoon of chipotle pepper
  • 2 tablespoons of fresh lemon juice
  • Salt and black pepper to season fishes

These ingredients are essential for a tasty and fulfilling spicy fish sandwich. You can find them at any local supermarket or grocery store. Make sure to choose fresh tilapia fillets or any other white fish that you prefer. It is important to wash the vegetables and fruits before using them in the recipe.

The Recipe How-To

“Calling all spice lovers – this Southwest Spicy Fish Sandwich is for you!”

Step 1: Prepare the fish

Begin by prepping the tilapia fillets, which are the star of the show. Mix garlic powder, chili powder, cumin, salt, and black pepper in a small bowl to create a seasoning blend. Rub this dry mix onto each side of the four tilapia fillets.

Next, add extra virgin olive oil and butter to a sauté pan over medium-high heat. Once melted and hot, cook your seasoned tilapia fillets for 2-3 minutes on each side until they’re crispy and golden brown.

Step 2: Prepare the bun

While your fish is cooking, slice four large hamburger buns in half horizontally. Brush them with melted butter and sprinkle with sesame seeds. Place the buns cut-side up on a baking sheet lined with parchment paper and toast until lightly golden brown.

Step 3: Prepare the chipotle mayonnaise

In a small mixing bowl, combine mayonnaise, finely chopped chipotle peppers, lemon juice, and a pinch of salt to create a spicy mayo that works wonders on this sandwich.

Step 4: Assemble the sandwich

Spread a generous amount of chipotle mayo onto both sides of each toasted bun. Then add a large leaf of romaine lettuce on top of the bottom bun followed by the crispy fish fillet.

Next up, slice 4 ounces of cheddar cheese into thin slices and place them over the warm fish so that it will melt slightly. Finally, top with the other half of your toasted bun and serve immediately.

That’s it! You have now mastered how to make an incredibly flavorful Southwest Spicy Fish Sandwich recipe that’s perfect for lunch or dinner.

Substitutions and Variations

If you’re looking to switch things up a bit with your Southwest Spicy Fish Sandwich Recipe, there are plenty of substitutions and variations that you can try.

Firstly, let’s talk about the fish fillet itself. While tilapia fillets are recommended for this recipe, you can certainly experiment with other white fish types such as cod, haddock or halibut. Additionally, if you want to make the sandwich even healthier, you can use an air fryer or bake the fish fillets instead of frying them in oil.

For those who prefer a milder spicy kick, you can reduce the amount of chipotle pepper used in the recipe. If, on the other hand, you love your food extra spicy, feel free to add more chipotle pepper or even some sliced jalapeño peppers to the mix.

If you’re not a fan of mayonnaise-based sauces, you can swap out the chipotle mayonnaise for a homemade chili mayo made with fresh spicy peppers blended with garlic powder and lemon juice. And for those who prefer a more classic condiment alongside their spicy fish sandwich, tartar sauce is always a great option.

Lastly, if you’re feeling adventurous and want to try something new, consider creating a southwestern baked fish sandwich or a blackened fish sandwich with Cajun-inspired seasonings. Or, if chicken is more your thing, try substituting the fish fillets for grilled or crispy chicken in a Southwest Chicken Sandwich.

Don’t be afraid to get creative and experiment with different flavors and ingredients. Who knows – maybe you’ll discover your new favorite sandwich recipe in the process!

Serving and Pairing

When it comes to serving the Southwest Spicy Fish Sandwich, there are a few options to consider. First and foremost, this sandwich is meant to be enjoyed hot and crispy, right out of the pan. However, if you need to prepare them ahead of time or simply have leftovers, they can be reheated in the oven, air fryer or microwave.

To pair with this spicy and robust sandwich, I would recommend serving a side of crispy cole slaw or kettle chips. The tangy and refreshing crunch of the cole slaw will balance out the heat of the chipotle mayo and spice blend on the fish. On the other hand, kettle chips provide a satisfying salty crunch that complements the Southwest spices used in this recipe.

If you are looking for something more substantial, consider serving alongside a cold beer or iced tea. The crisp bubbles of a lager or ale will help wash away the heat while the herbal notes in iced tea create a refreshing contrast to the spicy flavors.

Overall, whether you serve your Southwest Spicy Fish Sandwich with classic side dishes or cold beverages, it’s sure to be a crowd-pleaser. So get cooking and enjoy!

Make-Ahead, Storing and Reheating

If you’re planning to make these southwest spicy fish sandwiches ahead of time, it’s important to prepare the components separately to maintain their texture and flavor. Cook the fish fillets and refrigerate them in an airtight container for up to two days. The chipotle mayonnaise and tomatoes can be stored in the refrigerator for up to five days, while the lettuce can be washed and dried ahead of time, but should not be cut until ready to serve.

When it’s time to assemble the sandwiches, toast the buns, spread the chipotle mayo on both sides of the bun and layer with lettuce, tomato, and cheese. Place the cooked fish fillet on top and enjoy.

If you have leftover southwest spicy fish sandwiches, store them in an airtight container in the refrigerator for up to two days. To reheat, place them on a baking sheet in the oven at 350°F for about 10 minutes or heat them in the microwave briefly until heated through.

It’s worth noting that fried fish fillets are best served fresh as they can lose their crispiness when reheated. However, air-frying or baking them can help re-crisp them better than microwaving.

In conclusion, with proper storage and reheating techniques, you can still enjoy your delicious southwest spicy fish sandwich even a day or two after making it. Just make sure to reheat it properly so that you get to experience all of its amazing flavors.

Tips for Perfect Results

If you want to make the best southwest spicy fish sandwich recipe, a little bit of attention can go a long way. Here are some tips to help you achieve perfect results every time.

First and foremost, when grilling or frying the fish fillets, it’s essential to use the right cooking oil. Try using extra virgin olive oil or butter for a delicious flavor, but keep in mind that they have low smoke points. So, if you’re cooking over high heat, use an oil with a higher smoke point so that it won’t burn.

Next, season the fish fillets generously with garlic powder and chili powder before cooking them. For an extra kick of spice, add some chipotle pepper to the seasoning mix. Also, use fresh and spicy chili mayo as condiment since it will complement nicely with the spiciness of the fish.

When topping your sandwich, be sure to choose fresh and crisp ingredients. Opt for large leaves of romaine lettuce or iceberg lettuce instead of wilted greens. Add slices of cheddar cheese for additional flavor and texture.

If you’re not a fan of tilapia fillets or white fish in general, try using other types of fish like cod, salmon or sea bass. They work wonderfully in this recipe as well!

Finally, don’t forget to toast your hamburger buns before assembling them since it brings out more flavors from the bread and adds an extra layer of crunchy texture to your dish.

Following these tips can help ensure that your southwest spicy fish sandwich recipe turns out great every time!


As you embark on making this delicious Southwest Spicy Fish Sandwich Recipe, you may have some questions or concerns that need clarification. To alleviate any doubts or worries, I have compiled a list of frequently asked questions along with their corresponding answers. These FAQs will help ensure that your cooking experience runs smoothly, and the flavors of the southwest come to life in this spicy and crispy fish sandwich. Keep reading to learn more!

What is on the spicy fish sandwich?

If you’re looking to take your fish sandwich up a notch, try out this spicy and flavorful version! It features a crispy fish fillet that’s seasoned to perfection, then topped with fire-roasted jalapenos, shredded lettuce, tomato slices, and tartar sauce. All of this deliciousness is sandwiched between a toasted sesame bun for the ultimate bite. Give it a try and spice up your sandwich game.

What seasoning is on Arby’s spicy fish sandwich?

Arby’s Fiery Seasoning owes its spicy flavor to a blend of chili pepper and dehydrated cayenne pepper sauce, which are key components in the Spicy Fish Sandwich recipe. Despite being overshadowed by flavors of salt, garlic, and onion, these peppers add a fiery kick to the sandwich. However, if not applied in the right proportion, the heat level can be underwhelming.

What fish makes a good fish sandwich?

When it comes to frying fish for sandwiches, I find that using cod is a smart choice. One of the reasons for this is that it is an affordable option that has a delicate and soft texture that absorbs flavors well. To enhance the taste, I recommend briefly marinating the cod. If you’re looking for other types of fish to use, tilapia, halibut, snapper or catfish are also great options, though halibut can be pricier. This tip was last shared on March 5, 2021.

Who has a spicy fish sandwich?

The fish fillet at Arby’s is a delectably crispy and light meal, made even better with a flavorful blend of spices. The heat from the spice is balanced perfectly with the tangy tartar sauce and fresh veggies, creating a satisfying and refreshing taste. It’s unfortunate that the dish won’t be a permanent fixture on the menu, because I could definitely see myself ordering it time and time again.

Bottom Line

In conclusion, this Southwest Spicy Fish Sandwich recipe is the perfect addition to anyone’s culinary repertoire. Not only is it quick and easy to make, but it is packed full of delicious flavor that is sure to tantalize your taste buds. By following these simple steps, you can create a crispy, spicy fish fillet that will leave you wanting more.

With this recipe, you’ll have the option to customize the sandwich to your liking with the given substitutions and variations. And for those who are health-conscious, you can easily switch out a few ingredients for healthier alternatives.

So why not spice up your lunchtime routine and give this recipe a try? Whether it’s for a quick weekday lunch or a weekend gathering with friends and family, this Southwest Spicy Fish Sandwich recipe will be sure to impress. Give it a go and let me know what you think – I am confident that it’ll become a favorite in no time!

Southwest Spicy Fish Sandwich

Southwest Spicy Fish Sandwich Recipe

From cook’ Can purchase store-bought chipotle mayonnaise or see recipe below.
5 from 4 votes
Print Pin
Course: Main Course
Cuisine: American
Keyword: < 30 Mins, Lunch, Tilapia, Weeknight
Prep Time: 20 minutes
Cook Time: 6 minutes
Calories: 483.3kcal


  • 4 tilapia fillets
  • 4 large hamburger buns with sesame seeds
  • 4 large leaves romaine lettuce
  • 4 ounces cheddar cheese
  • 4 tablespoons chipotle mayonnaise (recipe below)
  • chipotle pepper, in adobe sauce (used to make chipotle mayo)
  • 1 tablespoon soft butter
  • 1 tablespoon emeril’s southwest seasoning (or see $notetemplate1$)
  • 2 tablespoons extra virgin olive oil


  • Heat olive oil on medium high in a large frying pan. Sprinkle tilapia fillets liberally with southwest seasoning. When oil is hot, add fillets. Cook 3 minutes on each side. Remove fish to a plate.
  • Slice cheese into thin slices. Make chipotle mayonnaise (see recipe below).
  • Heat grill pan to medium high. Lightly butter the buns and grill, buttered side down until browned. Add thinly sliced cheese to the bottom of each bun. Melt the cheese under a broiler or toaster oven and remove from oven. Add a fish filet to each bun. Place a romaine lettuce leaf on top of the fish. Add 1 tablespoon of chipotle mayonnaise to each bun top and place the bun on top of lettuce.
  • Chipotle Mayonnaise Recipe:
  • Place one 7 or 8 oz. can of chipotle peppers in adobe sauce in food processor. Pulse until peppers are well chopped. Add 3 tablespoons of the chipotle sauce to 1 cup of mayonnaise. Freeze or refrigerate remaining chipotle sauce for future use. Refrigerate remaining chipotle mayonnaise.

Your own notes


Serving: 832g | Calories: 483.3kcal | Carbohydrates: 45.7g | Protein: 19g | Fat: 27.7g | Saturated Fat: 10.2g | Cholesterol: 41.3mg | Sodium: 562.4mg | Fiber: 14.1g | Sugar: 11.2g